The critical importance of a well-annotated genome is emphasized by the advances
made by the recent reannotation of the honeybee ( Apis mellifera ) genome (Elsik
et al. 2014 ; Honeybee Genome Sequencing 2006 ). The A. mellifera genome was
one of the fi rst agriculturally important insect genomes to be sequenced. The reannotated
honeybee genome was driven by the generation of additional A. mellifera
genome sequences, which had marked impacts. The new honeybee genome
sequences increased the sizes of the contig N50 from 40 to 46 kb and scaffold N50